Description

Product Description :

5-Amino-1MQ 10mg/vial

5-Amino-1MQ, or 5-Amino-1-Methylquinoline Iodide, is a research-grade compound. It is a potent, selective inhibitor of nicotinamide N-methyltransferase (NNMT), acting through specific binding to the enzyme’s substrate-binding site. In cellular studies, 5-Amino-1MQ effectively reduces adipogenesis in 3T3-L1 cells and lowers 1-methylnicotinamide levels in adipocytes without affecting methyl transferases or enzymes involved in the NAD+ salvage pathway. Animal experiments demonstrate its efficacy in treating diet-induced obesity, muscle injury, and inhibiting ovarian cancer metastasis.

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